On May 1, 2026, Purdue Pharma permanently ceased operations. Knoa Pharma, a new and different company, will distribute medicines formerly distributed by Purdue Pharma. For inquiries about a Knoa Pharma or Purdue Pharma medicine, or to report an adverse event or product complaint, click here.

Knoa Pharma is committed to supporting healthcare professionals on the responsible use of our products.

Responsible Use of Opioids

For information on appropriate use and prescribing of opioid analgesics as well as the risks of opioids, prescription drug abuse, prescription drug monitoring programs, and the opioid analgesic Risk Evaluation and Mitigation Strategy (REMS), please see the resources available at Ask Knoa Medical.

Opioid Analgesic REMS

The U.S. Food and Drug Administration (FDA) has mandated that opioid analgesics have a Risk Evaluation and Mitigation Strategy (REMS) to help ensure that the benefits of the drug outweigh its risks.

doctor explaining to patient how to use medication
Opioid Analgesics logo

Opioid Analgesic REMS

One effort to address the misuse and abuse of opioids is the Risk Evaluation and Mitigation Strategy (REMS) for opioid analgesics.

A REMS is a program to manage known or potential serious risks associated with a drug product and is required by the U.S. Food and Drug Administration (FDA) to help ensure that a drug’s benefits outweigh its risks. The FDA has required a REMS for opioid analgesics.

healthcare professional using a tablet

For More Information on REMS

To download materials for healthcare professionals and materials for your patients, including a list of frequently asked questions, please click HERE.

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Opioids With Abuse-Deterrent Properties

Opioids with abuse-deterrent properties are not abuse-proof and they do not prevent the risk of addiction, overdose, or death. We are acutely aware of the public health risks these powerful medications create, especially when they are diverted, misused, and/or abused. Opioids with abuse-deterrent properties won’t stop all prescription opioid abuse, but they are one part of the comprehensive approach needed to address this complex public health issue.

For more information about Abuse-Deterrent Opioid Analgesics, please click HERE.

Safe Disposal of Opioids

When taking opioid medicines, it is important to advise patients to store medicine away from children and in a safe place to prevent stealing.

Also advise patients that expired, unwanted or unused medicine should be removed from the home as quickly as possible to help reduce the chance that others may accidentally take or intentionally misuse the medicine.

Additional information on medication disposal is available on the FDA’s website and the Opioid Analgesics REMS website.

Also visit the DEA’s website for more information about drug disposal, National Prescription Drug Take-Back Day events and to locate a DEA-authorized collector in your area.

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