Company-Sponsored Scientific Publications on Opioid Overdose Reversal
These company-sponsored publications are provided for scientific and informational purposes only. They are not intended as promotional communications and should not be interpreted as making or implying any claims about approved products.
Nalmefene HCl Injection
Pharmacology
Manuscripts
Date
Citation
Link
September 2024
Time Course of Reversal of Fentanyl Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene and Intramuscular and Intranasal Naloxone.
J Clin Pharmacol. 2025;65(2):206-216.
Cipriano A, Apseloff G, Kapil RP, He E, Shet M, Harris SC.
Abstracts
Date
Citation
Link
October 2024
Development of a Sensitive Method for the Detection and Quantitation of Nalmefene in Human Plasma Samples for Pharmacokinetic Analysis.
Abstract presented at American Association of Pharmaceutical Scientists annual meeting.
Bennett D, Chinnici C, Williard C, Shet MS.
Zurnai
Pharmacology
Manuscripts
Date
Citation
Link
July 2026
Development of a Nalmefene Formulation Suitable for a Community-Use Auto-Injector.
Br J Clin Pharmacol. 2026; 1-12.
Cipriano A, Shet MS, Huang H, et al.
August 2025
Reversal of Fentanyl-Induced Respiratory Depression in Healthy Subjects by Intramuscular Nalmefene Administered by Auto-Injector Versus Intranasal Naloxone.
J Clin Pharmacol. 2025;65(12):1661-1675.
Cipriano A, He E, Shet M, Apseloff G, Harris SC.
Abstracts
Date
Citation
Link
March 2026
Laypeople Express a Willingness and Comfort to Use Autoinjectors as an Option for Reversing the Symptoms of Opioid Overdoses.
American Journal of Health-System Pharmacy, 2025 ASHP Midyear Clinical Meeting Poster Abstracts, Volume 83, Issue Supplement_2, 6 March 2026.
Alfieri T, Erensen J.
Opioid Overdose Reversal / Opioid Antagonists
Real-World Studies
Manuscripts
Date
Citation
Link
Dec 2025
Use of Multiple Naloxone Administrations in the Emergency Department: A Retrospective Claims-Based Analysis.
J Emerg Med. 2025;79:111-122.
Rzasa Lynn R, Galinkin J, McClain M, Alfieri T.
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